Aggarwal, B. B. et al. (2004) Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res. 24, 2783–2840 (2004).
Alcendor RR, Gao S, Zhai P, et al. (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circulation Research. 2007;100:1512-1521
Anekonda TS. (2006) Resveratrol – a boon for treating Alzheimer’s disease? Brain Research Reviews. 2006; 52:316-326.
Aziz, M., Afaq, F. & Ahmad, N. (2004) Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin. Photochem. Photobiol. 81, 25–31 (2004).
Baur JA, Sinclair DA. (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nature Reviews. 2006; 5:493-506.
Boocock DJ, Faust GES, Patel KR, et al. (2007) Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemoprotective agent. Cancer Epidemiology, Biomarkers & Prevention. 2007; 16:1246-1252
Bielsalski HK. (2007) Polyphenols and inflammation: basic interactions. Current opinion in clinical nutrition and metabolic care. 2007; 10:724-728.
Baur JA, Pearson KJ, Price NL, et al. (2006) Resveratrol improves health and survival of mice on a high calorie diet. Nature. 2006; 444:337-342
Bradamante, S., Barenghi, L. & Villa, A. (2004) Cardiovascular protective effects of resveratrol. Cardiovasc. Drug Rev. 22, 169–188 (2004).
Chen, Y., Tseng, S. H., Lai, H. S. & Chen, W. J. (2004) Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice. Surgery 136, 57–66 (2004).
Chow HH, Garland LL, Heckman-Stoddard BM, et al. (2014) A pilot clinical study of resveratrol in postmenopausal women with high body mass index: effects on systemic sex steroid hormones. J Transl Med. 2014 Aug 14;12:223. doi: 10.1186/s12967-014-0223-0.
Das S, Das DK. (2007) Anti-inflammatory responses of resveratrol. Inflammation & Allergy – Drug Targets. 2007; 6:168-173.
Elmali, N. et al. (2005) Effect of resveratrol in experimental osteoarthritis in rabbits. Inflamm. Res. 54, 158–162 (2005).
Ghanim H, Sia CL, Abuaysheh S, et al. (2010) An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 2010 Sep; 95(9):E1-8. doi: 10.1210/jc.2010-0482.
Howitz K, Sinclair D. (2008) Xenohormesis: Sensing the Chemical Cues of Other Species. Cell. 2008; 133:387-391.
Howitz, K. T. et al. (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae life span. Nature 425, 191–196. 2003.
Jang, M. et al. (1997) Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275, 218–220 (1997).
Khanduja, K. L., Bhardwaj, A. & Kaushik, G. (2004) Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice. J. Nutr. Sci. Vitaminol. (Tokyo) 50, 61–65 (2004).
Kimura, Y. & Okuda, H. (2001) Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice. J. Nutr. 131, 1844–1849 (2001).
Lagouge M, Argmann C, Gerhart-Hines Z, et al. (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell. 2006; 127:1109-1122.
Lekakis, J. et al.(2005) Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur. J. Cardiovasc. Prev. Rehabil. 12, 596–600 (2005).
Li, Z. G. et al. (2002) Suppression of N-nitro somethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol. Carcinogenesis 23, 1531–1536 (2002).
Rahman I, Biswas SK, Kirkham PA (2006) Regulation of inflammation and redox signaling by dietary polyphenols. Biochemical Pharmacology. 2006; 72:1439-1452.
Renes J, Rosenow A, Roumans N, et al. (2014) Calorie restriction-induced changes in the secretome of human adipocytes, comparison with resveratrol-induced secretome effects. Biochim Biophys Acta. 2014 Sep; 1844(9):1511-22. doi: 10.1016/j.bbapap.2014.04.023.
Richard D. Semba, Luigi Ferrucci, Benedetta Bartali, et al. (2014) Resveratrol Levels and All-Cause Mortality in Older Community-Dwelling Adults. JAMA Intern Med. 2014; 174(7):1077-1084. doi: 10.1001/jamainternmed.2014.1582
Robb EL, Page MM, Wiens BE, Stuart JA. (2008) Molecular mechanisms of oxidative stress resistance induced by resveratrol: specific and progressive induction of MnSOD. Biochemical and Biophysical Research Communications. 2008; 367:406-412.
Schreiber L, McAnulty S, McAnulty L, et al. (2008) Resveratrol and catechin administration blunts exercise induced oxidative stress and cytokine IL-8. Paper presented at: American College of Sports Medicine Annual Meeting; May 28-31, 2008; Indianapolis, IN.
Siemann, E. H. & Creasy, L. L. (1992) Concentration of the phytoalexin resveratrol in wine. Am. J. Eno. Vitic. 43, 49–52 (1992).
Smoliga, J.M., Bost, J. and Maroon, J.C., (1997) Potential Benefits of Resveratrol Supplementation for Optimizing Health and Preventing Chronic Disease. Antiaging Therapeutics. Anti-Aging Ther, 1997, 11, 361-368
Smoliga JM, Bost J, Bost KM, Maroon JC. (2007) Three Months Oral Supplementation of a Unique Polyphenol Mixture Improves Physical and Neurocognitive Performance Indicators in Sedentary Adults. Paper presented at: Mid-Atlantic Regional Chapter of the American College of Sports Medicine; November 2-3, 2007; Harrisburg, PA.
Sunhee Shin, Jeong Hee Jeon, Dongsun Park, et al. (2008) Trans-resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo. January 2008, Volume 31, Issue 1, pp 83-87, 26 Mar 2008.
Szewczuk, L. M., Forti, L., Stivala, L. A. & Penning, T. M. (2004) Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents. J. Biol. Chem. 279, 22727–22737 (2004)
Tseng, S. H. et al. (2004) Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats. Clin. Cancer Res. 10, 2190–2202 (2004).
Wang, Z. et al. (2005) Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels. Int. J. Mol. Med. 16, 533–540 (2005).
Witte AV, Kerti L, Margulies DS, Flel A. (2014) Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults. J Neurosci. 2014 Jun 4;34(23): 7862-70. doi: 10.1523/JNEUROSCI.0385-14. 2014.
Wenzel E1, Somoza V. (2005) Metabolism and bioavailability of trans-resveratrol. Mol Nutr Food Res. 2005 May;49(5):472-81.
Wu RE, Huang WC, Liao CC, Chang YK, Kan NW, Huang CC. (2013) Resveratrol protects against physical fatigue and improves exercise performance in mice. Molecules. 2013 Apr 19;18(4):4689-702. doi: 10.3390/molecules18044689.
Valenzano, D. R. et al. (2006) Resveratrol prolongs lifespan and retards the onset of age-related markers in a shortlived vertebrate. Curr. Biol. 16, 296–300 (2006).
Professional Use Only
Food Supplements should not be used as a substitute for a varied diet
Any information or product suggested on this website is not intended to diagnose, treat, cure or prevent any medical condition. Never disregard medical advice or delay in seeking it because of something you have read on this website. Consult your primary healthcare physician before using any supplements or making any changes to your regime.