Black Seed Oil (Nigella Sativa) for Gastrointestinal Health

Black Seed Oil (Nigella Sativa) for Gastrointestinal Health

Jun 29, 2021


Nigella Sativa seeds and oil are carminative, which means they can support digestion and decrease digestive problems including gas, bloating, and stomach pain (1).

2012 study results indicate that thymoquinone (TQ) administration can prevent and improve murine DSS-induced colitis. These findings suggest that TQ could serve as a potential therapeutic agent for individuals with inflammatory bowel disease (2).


Black Seed Oil (Nigella Sativa) for Gastrointestinal Health


Black seed oil is often recommended and successfully used for intestinal parasites especially when combined with other natural remedies such as Wormwood (1). 

In an animal study, 20 rats with stomach ulcers were treated using Nigella sativa. As a result, about 83% of the rats recovered. In addition, black seed caused no side effects and turned to be as effective as a common medication used to treat stomach ulcers (3). 

According to a 2010 study, Nigella sativa oil was effective in overcoming the Helicobacter pylori infections, which is known to contribute to stomach ulcers (4). 

Another animal study showed that black seed and its active components prevented ulcer development and protected the lining of the stomach against the effects of alcohol. 

Black seed oil helps fight Candida overgrowth, thrush and fungal infections in the digestive tract. 

 Animal studies found that both thymoquinone and thymohydroquinone have antitumour activity and resulted in a 52 % decrease in abnormal cells (5). 

 In preliminary studies, Black seed oil was shown to inhibit the growth of colon tumour cells without causing any negative side effects. 

Internal and external use of Nigella sativa seeds or oil is safe. No cases of toxicity have been reported except for two cases of contact dermatitis. 



Related articles: 




  1. A Review of Medicinal Uses and Pharmacological Activities of Nigella sativa ( 
  2. Thymoquinone prevents and ameliorates dextran sulfate sodium-induced colitis in mice - PubMed ( 
  3. Comparative gastroprotective effects of natural honey, Nigella sativa and cimetidine against acetylsalicylic acid induced gastric ulcer in albino rats - PubMed ( 
  4. Comparative Study of Nigella sativa and Triple Therapy in Eradication of Helicobacter pylori in Patients with Non-Ulcer Dyspepsia - PMC ( 
  5. The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo - PubMed ( 



Any information or product suggested on this website is not intended to diagnose, treat, cure or prevent any medical condition. Never disregard medical advice or delay in seeking it because of something you have read on this website. Consult your primary healthcare physician before using any supplements or making any changes to your regime.

Image by KamranAydinov on Freepik

More Articles