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Curcumin is the active ingredient of the curry spice Turmeric, ground from the root of the plant called Curcuma Longa belonging to the ginger family. The medicinal properties of Turmeric and its main components called curcuminoids, primarily Curcumin, have been the subject of over 5000 peer-reviewed and published biomedical studies.
Asian culture use to believe Curcumin has important health benefits, especially natural anti-inflammatory qualities and it can act as a bacteria-killer in the stomach. In fact, its potential health effects were described thousands of years ago in India’s ancient Ayurvedic system of medicine where it was said to help with “stomach ailments, wound healing and blood cleansing.” Clinical research has now demonstrated that Curcumin may be beneficial for digestive health, by stimulating the gallbladder and helping produce bile. As bile helps digest fat, experts believe it can improve digestion; one study found it reduces symptoms of bloating and gas.
Among the occurring bioactive curcuminoids, Curcumin and its derivatives Demethoxycurcumin & Bisdemethoxycurcumin have specifically shown the strongest biological activity against oxidation (acting as natural potent radical scavengers). Tests in vitro showed that first Curcumin and then Demethoxycurcumin have the widest spectrum of activities including anti-inflammatory, antioxidant but also anticarcinogenic and antimutagenic activities.
Experts believe Curcumin as a supplement may improve rheumatoid arthritis symptoms and inflammatory skin conditions such as eczema. It may prevent blood clot formation and gallstones, help with stomach ulcers but also with diabetes, bacterial and viral infections and mental diseases, though scientific research has only just begun to prove the herb's efficacy for these ailments.
Case studies highlighted it may prevent and slow the progression of Alzheimer’s disease. The reports indicate specifically that extracts of Curcuma longa contain a number of natural agents that block the formation of beta-amyloid, the substance responsible for the plaques that slowly obstruct cerebral function in Alzheimer's disease.  It is also interesting to mention that Curcumin has long been used in Chinese medicine as a natural alternative to drugs for depression for its potential actions in the nervous system.
A 2009 study published in the journal, Biochemistry and Biophysical Research Community, explored how curcumin might also be valuable in helping with diabetes. A study in 2012 found how curcumin supplements were found to delay the onset of Type 2 diabetes among people with prediabetes.
“Over nine months, study participants were given either curcumin supplements or placebo capsules. Just over 16 percent of people taking the placebo pill were diagnosed with Type 2 diabetes by the end of the study, while no one taking curcumin was.Again, researchers chalk these results up to the anti-inflammatory and antioxidant powers of the compound”. 
Regarding the cancer-fighting properties of Curcumin supplementation, though exciting research is still ongoing, extremely promising clinical results have highlighted how curcumin can affect more than 100 different pathways, once it gets into the cell. More than decreasing inflammation, it has been found more specifically, to help inhibit the proliferation of tumour cells and to help prevent the development of additional blood supply necessary for cancer cell growth (angiogenesis) [3, 4]. In recent times, dozens of articles have reported the excellent performance of curcumin in brain tumors, especially how it helps inhibit the proliferation of glioma cells and in inducing apoptosis .
8 Effective Health Benefits of Turmeric and Curcumin
If studies show that Curcumin supplementation may help regulate chemical messengers that cause inflammation in the body, its beneficial properties also highly depend on its quality of curcuminoids and the bioavailability which is the main issue with most of Curcumin supplements.
Curcuminoids have naturally poor absorption into the bloodstream through the digestive tract. Their rapid metabolism in the liver and intestinal result therefore in low levels of bioavailability.
However, studies show that piperine, the active ingredient in black pepper enhances the serum concentration and bioavailability of curcumin by 2000%.
Piperine is a natural inhibitor of hepatic and intestinal glucuronidation, the main detoxification pathways in the body (liver detox process). Therefore, combined with Piperine, Curcumin is not destroyed by the digestive enzymes and can be absorbed into the blood system; and penetrate easily the brain for maximum effect. Studies showed that supplementation of curcuminoids combined with piperine showed especially significant reductions in markers of inflammation c-reactive protein and oxidative stress compared with placebo. 
Most of the products in the market do NOT contain piperine and have low levels of bioavailability. Besides, they don’t contain the 3 main curcuminoids, in fact 20% of turmeric and curcumin supplements delivered less than 15% of promised curcuminoid compounds.
It is important to look for high-quality supplements when it comes to curcumin.
HealthAid Curcumin 3* is standardised in its purest and concentrated form providing 95% of active curcuminoids especially its three main chemical compounds - Curcumin, Demethoxycurcumin, Bisdemethoxycurcumin - combined with the highest quality of Piperine extract to ensure optimum absorption and efficacy.
Healthaid Curcumin 3 helps support naturally inflammatory response for overall wellbeing.This nutritional supplement is ideal especially for those who wish to maintain a healthy digestive system, those with swollen joints, with inflammatory skin conditions and with pain caused by general inflammation in the body.
*Food Supplements should not be used as a substitute for a varied diet. If you are on prescribed medication, inform your doctor.
HealthAid Nutritionist / R&D Coordinator
 James A. Duke, Phd., in the October, 2007 issue of Alternative & Complementary Therapies, and summarized in the July, 2008, issue of the American Botanical Council publication HerbClip.
 Curcumin Extract for Prevention of Type 2 Diabetes, article published by the American Diabetes Association 2012 http://care.diabetesjournals.org/content/early/2012/07/02/dc12-0116
 Curcumin in various cancers. School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 702-701,
 Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.
 Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis Received: November 12, 2014; Accepted: December 29, 2014; Published Online: January 07, 2015 http://www.clinicalnutritionjournal.com/article/S0261-5614(15)00002-3/abstract